Link Reaction & Krebs Cycle

01Link Reaction & Krebs Cycle

Pyruvate transport

This section covers the active transport of pyruvate from the cytoplasm into the mitochondrial matrix.

From glycolysis to the mitochondrion

When oxygen is available, the pyruvate formed during glycolysis moves from the cytoplasm into a mitochondrion so that aerobic respiration can continue.

Pyruvate crosses the mitochondrial membranes and enters the mitochondrial matrix by active transport.

  • The movement is against a concentration gradient.
  • ATP is required for the transport process.
  • A membrane transport protein is involved.

Once pyruvate reaches the matrix, it can undergo the link reaction.

cytoplasmmitochondrialmatrixmitochondrialmembranestransport proteinpyruvateactive transportATP required

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