Preparing Organic Liquids

01Preparing Organic Liquids

Heating under reflux

This section covers heating an organic reaction mixture under reflux without losing volatile reactants.

Purpose of reflux

Heating under reflux allows an organic reaction mixture to be heated for an extended period while reducing the loss of volatile substances. Vapour rises into a vertical condenser, cools and returns to the reaction flask as liquid.

The preparation of an ester provides a suitable example. Ethanol and ethanoic acid can be heated with concentrated sulfuric acid to prepare ethyl ethanoate.

CHX3COOH+CHX3CHX2OHCHX3COOCHX2CHX3+HX2O\ce{CH3COOH + CH3CH2OH <=> CH3COOCH2CH3 + H2O}

Setting up the reaction

  1. Add 10 cm310\ \mathrm{cm^3} of ethanol and 12 cm312\ \mathrm{cm^3} of glacial ethanoic acid to a pear-shaped flask.
  2. Add 15 drops of concentrated sulfuric acid.
  3. Add a few anti-bumping granules.
  4. Fit the condenser vertically above the reaction flask.
  5. Partly immerse the flask in a water bath and heat the mixture under reflux for about 15 minutes.
  6. Stop heating and allow the mixture to cool.

Anti-bumping granules help the mixture boil more evenly by encouraging small bubbles rather than sudden large ones.

reaction mixtureanti-bumping granuleswater inwater outcondenseropenwater bathheat

Condenser and heating details

  • Cooling water enters through the lower condenser connection and leaves through the upper connection.
  • The top of the condenser remains open so that pressure cannot build inside the heated apparatus.
  • A water bath or electric heater avoids placing flammable organic liquids close to a naked flame.

Safety

  • Concentrated sulfuric acid and ethanoic acid are corrosive, so suitable eye and hand protection is required.
  • Ethanol is flammable and should be kept away from naked flames.
  • Ethyl ethanoate is flammable, toxic and strongly odorous, so it should be handled in a fume cupboard.
Exam Tip: In a reflux diagram, draw the condenser vertically and leave its upper end open. Show cooling water entering through the lower connection and leaving through the upper connection.

Create a free account to continue

Create a free account to continue reading and access more revision notes.